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Catalog of the NINDS Human Cell and Data Repository

Publications

2023

1. Ahn HW, ..., Levin HL. Retrotransposon insertions associated with risk of neurologic and psychiatric diseases. EMBO Rep (2023 Jan 9)

[PubMed 36367221] [PMC free article] [DOI 10.15252/embr.202255197] [Related External Line IDs: NCRM-1 (NHCDR line ND50028) (RMP Cell Line ID)]

2. Allen AG, ..., Zuris JA. A highly efficient transgene knock-in technology in clinically relevant cell types. Nat Biotechnol (2023 May 1)

[PubMed 37127662] [DOI 10.1038/s41587-023-01779-8] [Related Cell Line IDs: NH50191]

3. Arslan U, ..., Orlova VV. Vascularized hiPSC-derived 3D cardiac microtissue on chip. Stem Cell Reports (2023 Jul 11)

[PubMed 37390826] [PMC free article] [DOI 10.1016/j.stemcr.2023.06.001] [Related External Line IDs: NCRM-1 (NHCDR line ND50028) (RMP Cell Line ID)]

4. Becerra-Calixto A, ..., Soto C. Lewy Body-like Pathology and Loss of Dopaminergic Neurons in Midbrain Organoids Derived from Familial Parkinson's Disease Patient. Cells (2023 Feb 15)

[PubMed 36831291] [PMC free article] [DOI 10.3390/cells12040625] [Related Subject IDs: NDS00201]

5. Chin RM, ..., Hertz NT. Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models. bioRxiv (2023 Feb 15)

[PubMed 36824886] [PMC free article] [DOI 10.1101/2023.02.14.528378] [Related Cell Line IDs: ND50050]

6. Fang L, ..., Wang K. Haplotyping SNPs for allele-specific gene editing of the expanded huntingtin allele using long-read sequencing. HGG Adv (2023 Jan 12)

[PubMed 36262216] [PMC free article] [DOI 10.1016/j.xhgg.2022.100146] [Related Cell Line IDs: ND33392]

7. Fukushi M, ..., Sakaguchi T. Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection. PLoS One (2023)

[PubMed 37352136] [PMC free article] [DOI 10.1371/journal.pone.0287545] [Related Cell Line IDs: ND29149, ND29510, ND29563, ND29689, ND39025, ND39026, ND39027, ND41003]

8. Gutiérrez-Garcia R, ..., Vilchez D. G3BP1-dependent mechanism suppressing protein aggregation in Huntington's models and its demise upon stress granule assembly. Hum Mol Genet (2023 May 5)

[PubMed 36611004] [PMC free article] [DOI 10.1093/hmg/ddac304] [Related Cell Line IDs: ND36999, ND42242]

9. Huang H, ..., Lennikov A. Association of Placental Growth Factor and Angiopoietin in Human Retinal Endothelial Cell-Pericyte co-Cultures and iPSC-Derived Vascular Organoids. Curr Eye Res (2023 Mar)

[PubMed 36458540] [PMC free article] [DOI 10.1080/02713683.2022.2149808] [Related Cell Line IDs: ND50018] [Related Subject IDs: NDS00249]

10. Hung ST, ..., Ichida JK. PIKFYVE inhibition mitigates disease in models of diverse forms of ALS. Cell (2023 Feb 16)

[PubMed 36754049] [PMC free article] [DOI 10.1016/j.cell.2023.01.005] [Related Cell Line IDs: ND35663, ND39034, ND41865, ND50000, ND50007]

11. Iba M, ..., Masliah E. Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD. Sci Transl Med (2023 May 10)

[PubMed 37163617] [DOI 10.1126/scitranslmed.abq6089] [Related RUIDs: NN0004337, NN0004344]

12. Jangir H, ..., Hickman JJ. Mimicking the Tendon Microenvironment to Enhance Skeletal Muscle Adhesion and Longevity in a Functional Microcantilever Platform. ACS Biomater Sci Eng (2023 Aug 14)

[PubMed 37462389] [PMC free article] [DOI 10.1021/acsbiomaterials.3c00235] [Related Cell Line IDs: ND41865]

13. Joachimiak P, ..., Fiszer A. Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models. BMC Biol (2023 Feb 1)

[PubMed 36726088] [PMC free article] [DOI 10.1186/s12915-023-01515-3] [Related Cell Line IDs: ND42222]

14. Kalra J, ..., Kalra J. Crosslink between mutations in mitochondrial genes and brain disorders: implications for mitochondrial-targeted therapeutic interventions. Neural Regen Res (2023 Jan)

[PubMed 35799515] [PMC free article] [DOI 10.4103/1673-5374.343884] [Related External Line IDs: ND1.4 (NHCDR line ND50021) (RMP Cell Line ID)]

15. Kamienieva I, ..., Szczepanowska J. In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts. Biochim Biophys Acta Mol Basis Dis (2023 Oct)

[PubMed 37302428] [DOI 10.1016/j.bbadis.2023.166787] [Related Cell Line IDs: ND29543, ND30171, ND37731]

16. Kim MS, ..., Lee G. Advanced human iPSC-based preclinical model for Parkinson's disease with optogenetic alpha-synuclein aggregation. Cell Stem Cell (2023 Jul 6)

[PubMed 37339636] [PMC free article] [DOI 10.1016/j.stem.2023.05.015] [Related Cell Line IDs: ND27760]

17. Krzystek TJ, ..., Gunawardena S. HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury. Autophagy (2023 Apr)

[PubMed 36048753] [PMC free article] [DOI 10.1080/15548627.2022.2119351] [Related Cell Line IDs: ND38555]

18. Lee SW, ..., Yoo AS. Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease. Res Sq (2023 May 9)

[PubMed 37214956] [PMC free article] [DOI 10.21203/rs.3.rs-2815300/v1] [Related Cell Line IDs: ND30013, ND33947]

19. Lee Y, ..., Seong IS. Huntingtin turnover: modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550. Hum Mol Genet (2023 Jan 1)

[PubMed 35908190] [DOI 10.1093/hmg/ddac165] [Related Cell Line IDs: ND36997, ND36998, ND36999, ND38548, ND38555]

20. Leon KE, ..., Ott M. Nuclear accumulation of host transcripts during Zika Virus Infection. PLoS Pathog (2023 Jan)

[PubMed 36603024] [PMC free article] [DOI 10.1371/journal.ppat.1011070] [Related Cell Line IDs: ND31845]

21. Linares GR, ..., Ichida JK. SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS. Cell Stem Cell (2023 Feb 2)

[PubMed 36736291] [PMC free article] [DOI 10.1016/j.stem.2023.01.005] [Related Cell Line IDs: ND35658, ND35659, ND35663, ND39034, ND41865, ND50000, ND50007, ND50073, ND50082]

22. Masmoudi F, ..., Buti L. Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery. Cells (2023 Apr 12)

[PubMed 37190047] [PMC free article] [DOI 10.3390/cells12081138] [Related External Line IDs: NCRM-3 (NHCDR line ND50029) (RMP Cell Line ID)]

23. Mesa H, ..., Zhang Q. Human neurons lacking amyloid precursor protein exhibit cholesterol-associated developmental and presynaptic deficits. J Cell Physiol (2023 Mar 26)

[PubMed 36966431] [DOI 10.1002/jcp.30999] [Related Cell Line IDs: ND50022]

24. Mubariz F, ..., Awad O. Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson's disease. Front Neurosci (2023)

[PubMed 37332877] [PMC free article] [DOI 10.3389/fnins.2023.1152503] [Related Cell Line IDs: NH50142, NH50143, NH50183, NH50186, NH50187]

25. Nim S, ..., Kim PM. Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson's disease. Nat Commun (2023 Apr 19)

[PubMed 37076542] [PMC free article] [DOI 10.1038/s41467-023-37464-2] [Related Cell Line IDs: ND27760]

26. Nimbalkar S, ..., Hickman JJ. Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing. Front Cell Dev Biol (2023)

[PubMed 36936691] [PMC free article] [DOI 10.3389/fcell.2023.1011145] [Related Cell Line IDs: ND41865]

27. Oh M, ..., Jeon YJ. Neuroprotective Effects of Licochalcone D in Oxidative-Stress-Induced Primitive Neural Stem Cells from Parkinson's Disease Patient-Derived iPSCs. Biomedicines (2023 Jan 16)

[PubMed 36672736] [PMC free article] [DOI 10.3390/biomedicines11010228] [Related Cell Line IDs: ND38262]

28. Paul S, ..., Pulst SM. Staufen Impairs Autophagy in Neurodegeneration. Ann Neurol (2023 Feb)

[PubMed 36151701] [PMC free article] [DOI 10.1002/ana.26515] [Related Cell Line IDs: ND29510, ND34769, ND38530, ND42504, ND42506]

29. Sharma SD, ..., Chattarji S. Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons. Cell Rep (2023 Apr 25)

[PubMed 37018073] [PMC free article] [DOI 10.1016/j.celrep.2023.112344] [Related Cell Line IDs: ND30625]

30. Smith LJ, ..., Schapira AHV. The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines. Hum Mol Genet (2023 Feb 19)

[PubMed 36130205] [PMC free article] [DOI 10.1093/hmg/ddac233] [Related Cell Line IDs: ND41016] [Related Subject IDs: NDS00203]

31. Svrzikapa N, ..., Boyanapalli R. Full-Length Transcript Phasing with Third-Generation Sequencing. Methods Mol Biol (2023)

[PubMed 36335491] [DOI 10.1007/978-1-0716-2819-5_3] [Related Cell Line IDs: ND30259]

32. Travaglio M, ..., Martins LM. Increased cysteine metabolism in PINK1 models of Parkinson's disease. Dis Model Mech (2023 Jan 1)

[PubMed 36695500] [PMC free article] [DOI 10.1242/dmm.049727] [Related Subject IDs: NDS00227]

33. Tristan CA, ..., Singeç I. Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail. Nat Protoc (2023 Jan)

[PubMed 36261632] [DOI 10.1038/s41596-022-00753-z] [Related Cell Line IDs: ND50038]

34. Tufi R, ..., Briston T. High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy. SLAS Discov (2023 Apr)

[PubMed 36608804] [DOI 10.1016/j.slasd.2022.12.004] [Related Cell Line IDs: ND29369, ND29543, ND30171, ND31618, ND34769, ND34770, ND36320, ND40067, ND40078, NH50289] [Related RUIDs: NN0004771]

35. Wang H, ..., Dawson TM. Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons. bioRxiv (2023 Jun 26)

[PubMed 37425943] [PMC free article] [DOI 10.1101/2023.06.23.546087] [Related RUIDs: NN0005032, NN0005033]

36. Woo E, ..., Konrad C. Machine learning approaches based on fibroblast morphometry do not predict ALS. Neurobiol Aging (2023 Oct)

[PubMed 37473581] [DOI 10.1016/j.neurobiolaging.2023.06.010] [Related Cell Line IDs: ND29149, ND29422, ND29774, ND39022, ND39023]

37. Wu J, ..., Tang Y. Transcription Factor-Mediated Differentiation of Motor Neurons from Human Pluripotent Stem Cells. Methods Mol Biol (2023)

[PubMed 36513936] [DOI 10.1007/978-1-0716-2811-9_16] [Related Cell Line IDs: ND35664]

38. Yoo M, ..., Junn E. MicroRNA-593-5p contributes to cell death following exposure to 1-methyl-4-phenylpyridinium by targeting PTEN-induced putative kinase 1. J Biol Chem (2023 May)

[PubMed 37060996] [PMC free article] [DOI 10.1016/j.jbc.2023.104709] [Related Cell Line IDs: ND41865] [Related Subject IDs: NDS00159]

39. Ziff OJ, ..., Patani R. Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition. Neuron (2023 Oct 4)

[PubMed 37480846] [DOI 10.1016/j.neuron.2023.06.019] [Related Cell Line IDs: ND41866]

2022

40. Agten H, ..., Bloemen V. In vitro and in vivo evaluation of 3D constructs engineered with human iPSC-derived chondrocytes in gelatin methacryloyl hydrogel. Biotechnol Bioeng (2022 Oct)

[PubMed 35781799] [DOI 10.1002/bit.28168] [Related External Line IDs: CY2 (NHCDR line ND50020) (RMP Cell Line ID)]

41. Araújo B, ..., Teixeira FG. Neuroinflammation and Parkinson's Disease-From Neurodegeneration to Therapeutic Opportunities. Cells (2022 Sep 17)

[PubMed 36139483] [PMC free article] [DOI 10.3390/cells11182908] [Related Cell Line IDs: ND36091, ND39528, ND39896, ND50050, ND50085]

42. Autar K, ..., Hickman JJ. A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders. Stem Cell Reports (2022 Jan 11)

[PubMed 34942087] [PMC free article] [DOI 10.1016/j.stemcr.2021.11.009] [Related Cell Line IDs: ND41865]

43. Badu-Mensah A, ..., Hickman JJ. ALS mutations in both human skeletal muscle and motoneurons differentially affects neuromuscular junction integrity and function. Biomaterials (2022 Oct)

[PubMed 36084484] [DOI 10.1016/j.biomaterials.2022.121752] [Related Cell Line IDs: ND35662, ND39032, ND41865]

44. Bartalska K, ..., Siegert S. A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation. iScience (2022 Jul 15)

[PubMed 35789843] [PMC free article] [DOI 10.1016/j.isci.2022.104580] [Related External Line IDs: NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)] [Related RUIDs: CR0000005]

45. Burkhanova U, ..., Leir SH. Enhancement of airway epithelial cell differentiation by pulmonary endothelial cell co-culture. Stem Cell Res (2022 Dec)

[PubMed 36395690] [PMC free article] [DOI 10.1016/j.scr.2022.102967] [Related External Line IDs: ND1.4 (NHCDR line ND50021) (RMP Cell Line ID)] [Related RUIDs: CR0000011]

46. Chedid J, ..., Dzamko N. A small molecule toll-like receptor antagonist rescues α-synuclein fibril pathology. J Biol Chem (2022 Aug)

[PubMed 35841928] [PMC free article] [DOI 10.1016/j.jbc.2022.102260] [Related Cell Line IDs: ND29494]

47. Cho IK, ..., Chan AWS. Suppression of trinucleotide repeat expansion in spermatogenic cells in Huntington's disease. J Assist Reprod Genet (2022 Oct)

[PubMed 36066723] [PMC free article] [DOI 10.1007/s10815-022-02594-x] [Related Cell Line IDs: ND36999, ND38547, ND41658]

48. Cui H, ..., Ding B. Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system. STAR Protoc (2022 Dec 16)

[PubMed 36386872] [PMC free article] [DOI 10.1016/j.xpro.2022.101813] [Related Subject IDs: NDS00301, NDS00305]

49. Dang X, ..., Dorn GW 2nd. Mitochondrial Phenotypes in Genetically Diverse Neurodegenerative Diseases and Their Response to Mitofusin Activation. Cells (2022 Mar 21)

[PubMed 35326504] [PMC free article] [DOI 10.3390/cells11061053] [Related Cell Line IDs: ND29510, ND29969, ND33879, ND34730, ND34732, ND34733, ND34769, ND36320, ND40066]

50. Fang L, ..., Wang K. DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing. Genome Biol (2022 Apr 28)

[PubMed 35484600] [PMC free article] [DOI 10.1186/s13059-022-02670-6] [Related Cell Line IDs: ND30422, ND30626]

51. Hallacli E, ..., Khurana V. The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell (2022 Jun 9)

[PubMed 35688132] [PMC free article] [DOI 10.1016/j.cell.2022.05.008] [Related Cell Line IDs: ND34391] [Related Subject IDs: NDS00201]

52. Hawkins S, ..., Bhinge A. Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis. Stem Cell Reports (2022 Jul 12)

[PubMed 35750046] [PMC free article] [DOI 10.1016/j.stemcr.2022.05.019] [Related Cell Line IDs: ND35663]

53. Hübschmann V, ..., Siegert S. Assessing human iPSC-derived microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assay. STAR Protoc (2022 Dec 16)

[PubMed 36595902] [PMC free article] [DOI 10.1016/j.xpro.2022.101866] [Related External Line IDs: NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)] [Related RUIDs: CR0000005]

54. Kandasamy P, ..., Vargeese C. Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS. Nucleic Acids Res (2022 Jun 10)

[PubMed 35106589] [PMC free article] [DOI 10.1093/nar/gkac037] [Related Cell Line IDs: ND50000] [Related External Line IDs: TALS9-9.3 (NHCDR line ND50000) (Target ALS ID)]

55. Keller CG, ..., Sivasankaran R. An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion. Nat Commun (2022 Mar 3)

[PubMed 35241644] [PMC free article] [DOI 10.1038/s41467-022-28653-6] [Related Cell Line IDs: ND31551]

56. Killoy KM, ..., Vargas MR. NR1D1 downregulation in astrocytes induces a phenotype that is detrimental to cocultured motor neurons. FASEB J (2022 Apr)

[PubMed 35319791] [PMC free article] [DOI 10.1096/fj.202101275R] [Related Cell Line IDs: ND38555] [Related RUIDs: FA0000011]

57. Knittel J, ..., Brafman DA. A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes. STAR Protoc (2022 Sep 16)

[PubMed 36035791] [PMC free article] [DOI 10.1016/j.xpro.2022.101632] [Related Cell Line IDs: ND50028]

58. Leibel SL, ..., Post M. Metabolomic profiling of human pluripotent stem cell differentiation into lung progenitors. iScience (2022 Feb 18)

[PubMed 35198866] [PMC free article] [DOI 10.1016/j.isci.2022.103797] [Related Cell Line IDs: ND50028]

59. Linville RM, ..., Searson PC. Brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington's disease. Fluids Barriers CNS (2022 Jun 30)

[PubMed 35773691] [PMC free article] [DOI 10.1186/s12987-022-00347-7] [Related RUIDs: NN0003930]

60. Liu Y, ..., Vargeese C. Preclinical evaluation of WVE-004, aninvestigational stereopure oligonucleotide forthe treatment of C9orf72-associated ALS or FTD. Mol Ther Nucleic Acids (2022 Jun 14)

[PubMed 35592494] [PMC free article] [DOI 10.1016/j.omtn.2022.04.007] [Related Cell Line IDs: ND50000] [Related External Line IDs: TALS9-9.3 (NHCDR line ND50000) (Target ALS ID)]

61. Ma XR, ..., Gitler AD. TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature (2022 Mar)

[PubMed 35197626] [PMC free article] [DOI 10.1038/s41586-022-04424-7] [Related Subject IDs: NDS00209, NDS00262]

62. Mao Q, ..., Schnorrer F. Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers. Elife (2022 Aug 3)

[PubMed 35920628] [PMC free article] [DOI 10.7554/eLife.76649] [Related External Line IDs: NCRM-1 (NHCDR line ND50028) (RMP Cell Line ID)]

63. Morais RDVS, ..., Vallès A. Functional Intercellular Transmission of miHTT via Extracellular Vesicles: An In Vitro Proof-of-Mechanism Study. Cells (2022 Sep 3)

[PubMed 36078156] [PMC free article] [DOI 10.3390/cells11172748] [Related Cell Line IDs: ND42229]

64. Nath S, ..., Truant R. Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline. Hum Genome Var (2022 Apr 14)

[PubMed 35422034] [PMC free article] [DOI 10.1038/s41439-022-00188-8] [Related Cell Line IDs: ND30014, ND33391]

65. Novak G, ..., Skupin A. Generation of two human induced pluripotent stem cell lines from fibroblasts of Parkinson's disease patients carrying the ILE368ASN mutation in PINK1 (LCSBi002) and the R275W mutation in Parkin (LCSBI004). Stem Cell Res (2022 May)

[PubMed 35378365] [DOI 10.1016/j.scr.2022.102765] [Related Cell Line IDs: ND27760, ND29369, ND40066]

66. Novak G, ..., Skupin A. Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease. Commun Biol (2022 Jan 13)

[PubMed 35027645] [PMC free article] [DOI 10.1038/s42003-021-02973-7] [Related Cell Line IDs: ND40066]

67. Oh YM, ..., Yoo AS. Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy. Nat Neurosci (2022 Nov)

[PubMed 36303071] [PMC free article] [DOI 10.1038/s41593-022-01185-4] [Related Cell Line IDs: ND30013, ND33947]

68. Ojha R, ..., Lu B. Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells. Dev Cell (2022 Jan 24)

[PubMed 35077680] [PMC free article] [DOI 10.1016/j.devcel.2021.12.020] [Related Cell Line IDs: ND29510]

69. Pantazis CB, ..., Merkle FT. A reference human induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell (2022 Dec 1)

[PubMed 36459969] [PMC free article] [DOI 10.1016/j.stem.2022.11.004] [Related Cell Line IDs: ND50003, ND50004] [Related RUIDs: NN0003932, NN0004297]

70. Park HJ, ..., Song J. SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington's disease. NPJ Regen Med (2022 Jan 19)

[PubMed 35046408] [PMC free article] [DOI 10.1038/s41536-021-00198-0] [Related Cell Line IDs: ND41656]

71. Park HJ, ..., Song J. Author Correction : SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington's disease. NPJ Regen Med (2022 Apr 21)

[PubMed 35449161] [PMC free article] [DOI 10.1038/s41536-022-00219-6] [Related Cell Line IDs: ND41656]

72. Pediaditakis I, ..., Karalis K. A microengineered Brain-Chip to model neuroinflammation in humans. iScience (2022 Aug 19)

[PubMed 35982785] [PMC free article] [DOI 10.1016/j.isci.2022.104813] [Related Cell Line IDs: ND50028]

73. Rumsey JW, ..., Hickman JJ. Classical Complement Pathway Inhibition in a "Human-On-A-Chip" Model of Autoimmune Demyelinating Neuropathies. Adv Ther (Weinh) (2022 Jun)

[PubMed 36211621] [PMC free article] [DOI 10.1002/adtp.202200030] [Related Cell Line IDs: ND41866]

74. Rusilowicz-Jones EV, ..., Clague MJ. Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy. Life Sci Alliance (2022 Feb)

[PubMed 34844982] [PMC free article] [DOI 10.26508/lsa.202101287] [Related Cell Line IDs: ND29510, ND30171, ND40067]

75. Sandhurst ES, ..., Francis KR. Nanoarchitectonics of a Microsphere-Based Scaffold for Modeling Neurodevelopment and Neurological Disease. ACS Appl Bio Mater (2022 Feb 21)

[PubMed 35045249] [PMC free article] [DOI 10.1021/acsabm.1c01012] [Related External Line IDs: NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)]

76. Sears KE, ..., Jensen J. Controlling neural territory patterning from pluripotency using a systems developmental biology approach. iScience (2022 Apr 15)

[PubMed 35434550] [PMC free article] [DOI 10.1016/j.isci.2022.104133] [Related Cell Line IDs: ND50025, ND50028, ND50030, ND50031] [Related External Line IDs: NCRM-1 (NHCDR line ND50028) (RMP Cell Line ID), NCRM-2 (NHCDR line ND50030) (RMP Cell Line ID), NCRM-4 (NHCDR line ND50025) (RMP Cell Line ID), NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)]

77. Sen T, ..., Thummer RP. CRISPR and iPSCs: Recent Developments and Future Perspectives in Neurodegenerative Disease Modelling, Research, and Therapeutics. Neurotox Res (2022 Oct)

[PubMed 36044181] [PMC free article] [DOI 10.1007/s12640-022-00564-w] [Related Cell Line IDs: ND42222]

78. Sheta R, ..., Oueslati A. Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons. Sci Rep (2022 Oct 13)

[PubMed 36229560] [PMC free article] [DOI 10.1038/s41598-022-22158-4] [Related Cell Line IDs: ND36091, ND38554]

79. Stojkovska I, ..., Mazzulli JR. Rescue of α-synuclein aggregation in Parkinson's patient neurons by synergistic enhancement of ER proteostasis and protein trafficking. Neuron (2022 Feb 2)

[PubMed 34793693] [PMC free article] [DOI 10.1016/j.neuron.2021.10.032] [Related Cell Line IDs: ND34391, ND34982]

80. Su PY, ..., Allikmets R. Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture. Stem Cell Res (2022 Dec)

[PubMed 36455383] [PMC free article] [DOI 10.1016/j.scr.2022.102973] [Related RUIDs: FA0000010]

81. Su X, ..., Zhong G. Evidence for cGAS-STING Signaling in the Female Genital Tract Resistance to Chlamydia trachomatis Infection. Infect Immun (2022 Feb 17)

[PubMed 34978925] [PMC free article] [DOI 10.1128/iai.00670-21] [Related External Line IDs: CY2 (NHCDR line ND50020) (RMP Cell Line ID)]

82. Torriano S, ..., Farber DB. CRISPR-AsCas12a Efficiently Corrects a GPR143 Intronic Mutation in Induced Pluripotent Stem Cells from an Ocular Albinism Patient. CRISPR J (2022 Jun)

[PubMed 35686978] [PMC free article] [DOI 10.1089/crispr.2021.0110] [Related RUIDs: FA0000010]

83. Wu CI, ..., Young-Pearse TL. APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons. Mol Psychiatry (2022 Apr)

[PubMed 35194165] [PMC free article] [DOI 10.1038/s41380-022-01454-5] [Related Cell Line IDs: ND50026, ND50027]

2021

84. Al-Ahmad AJ, ..., Karamyan VT. Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model. J Neuroendocrinol (2021 Feb)

[PubMed 33506602] [PMC free article] [DOI 10.1111/jne.12931] [Related Cell Line IDs: ND41865]

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86. Burbulla LF, ..., Krainc D. Direct targeting of wild-type glucocerebrosidase by antipsychotic quetiapine improves pathogenic phenotypes in Parkinson's disease models. JCI Insight (2021 Oct 8)

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87. Cai J, ..., Iacovitti L. A stress-free strategy to correct point mutations in patient iPS cells. Stem Cell Res (2021 May)

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88. Chang KH, ..., Lin CH. In vitro genome editing rescues parkinsonism phenotypes in induced pluripotent stem cells-derived dopaminergic neurons carrying LRRK2 p.G2019S mutation. Stem Cell Res Ther (2021 Sep 22)

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89. Ciesiolka A, ..., Fiszer A. Artificial miRNAs targeting CAG repeat expansion in ORFs cause rapid deadenylation and translation inhibition of mutant transcripts. Cell Mol Life Sci (2021 Feb)

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90. de Rus Jacquet A, ..., O'Shea EK. The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease. Elife (2021 Sep 30)

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91. Deus CM, ..., Oliveira PJ. Corrigendum to 'A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients'. [Redox Biology 45 (2021) 102037]. Redox Biol (2021 Nov)

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92. Diao X, ..., Mukherjee A. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology. Cells (2021 Sep 13)

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93. Ding B, ..., Zhang CL. Disease Modeling with Human Neurons Reveals LMNB1 Dysregulation Underlying DYT1 Dystonia. J Neurosci (2021 Mar 3)

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95. Fukusumi H, ..., Kanemura Y. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio (2021 Feb)

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96. Gandelman M, ..., Scoles DR. The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy. J Biol Chem (2021 Oct)

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97. Gaweda-Walerych K, ..., Zekanowski C. Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency. Front Mol Neurosci (2021)

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98. Gilmozzi V, ..., Zanon A. Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture. Front Cell Dev Biol (2021)

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99. Harley J, ..., Patani R. TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain. Brain Commun (2021)

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100. Hörner SJ, ..., Rudolf R. hiPSC-Derived Schwann Cells Influence Myogenic Differentiation in Neuromuscular Cocultures. Cells (2021 Nov 24)

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101. Hu D, ..., Qi X. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun (2021 Sep 6)

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102. Jo J, ..., Je HS. Lewy Body-like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α-Synuclein Mutations. Ann Neurol (2021 Sep)

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103. Kerschner JL, ..., Harris A. OTX2 regulates CFTR expression during endoderm differentiation and occupies 3' cis-regulatory elements. Dev Dyn (2021 May)

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104. Killoy KM, ..., Vargas MR. Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model. FASEB J (2021 Feb)

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105. Kim H, ..., Seol W. Ciliogenesis is Not Directly Regulated by LRRK2 Kinase Activity in Neurons. Exp Neurobiol (2021 Jun 30)

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106. Li L, ..., Wang X. A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation. Nat Metab (2021 Sep)

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107. Liu Y, ..., Brown RH Jr. Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models. Nat Commun (2021 Feb 8)

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108. Lynch EM, ..., Suzuki M. Transcriptome analysis using patient iPSC-derived skeletal myocytes: Bet1L as a new molecule possibly linked to neuromuscular junction degeneration in ALS. Exp Neurol (2021 Nov)

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109. Mathieu C, ..., Porotto M. Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain. mBio (2021 Jun 29)

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110. Mazurek S, ..., Wiznerowicz M. Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs. Cells (2021 Jul 29)

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111. McAlpine CS, ..., Swirski FK. Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature (2021 Jul)

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112. Mohamed NV, ..., Durcan TM. Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy. Brain Commun (2021)

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113. Moreira L, ..., Fraga S. How can exposure to engineered nanomaterials influence our epigenetic code? A review of the mechanisms and molecular targets. Mutat Res Rev Mutat Res (2021 Jul-Dec)

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114. Namboori SC, ..., Bhinge A. Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons. Stem Cell Reports (2021 Dec 14)

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115. Novak G, ..., Skupin A. Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006). Stem Cell Res (2021 Dec)

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116. Novak G, ..., Skupin A. Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007). Stem Cell Res (2021 Dec)

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117. Otake K, ..., Iwata H. Quantitative comparison of the mRNA content of human iPSC-derived motor neurons and their extracellular vesicles. FEBS Open Bio (2021 Feb)

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118. Paul S, ..., Pulst SM. Staufen1 in Human Neurodegeneration. Ann Neurol (2021 Jun)

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120. Pereira JD, ..., Wainger BJ. Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions. Nat Commun (2021 Aug 6)

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122. Ramos-Gonzalez P, ..., Cavaliere F. Astrocytic atrophy as a pathological feature of Parkinson's disease with LRRK2 mutation. NPJ Parkinsons Dis (2021 Mar 30)

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123. Ren J, ..., Tang Y. A Step-by-Step Refined Strategy for Highly Efficient Generation of Neural Progenitors and Motor Neurons from Human Pluripotent Stem Cells. Cells (2021 Nov 9)

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124. Simkin D, ..., Kiskinis E. Dyshomeostatic modulation of Ca(2+)-activated K(+) channels in a human neuronal model of KCNQ2 encephalopathy. Elife (2021 Feb 5)

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125. Simone R, ..., de Silva R. MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature (2021 Jun)

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126. Singh T, ..., Carlisle DL. Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated. Sci Rep (2021 Sep 23)

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127. Smith VM, ..., Hickman JJ. A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics. Front Cell Dev Biol (2021)

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128. Sogorb-Gonzalez M, ..., Vallès A. Secreted therapeutics: monitoring durability of microRNA-based gene therapies in the central nervous system. Brain Commun (2021)

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129. Sonobe Y, ..., Kratsios P. A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nat Commun (2021 Oct 15)

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130. Stabley DL, ..., Butchbach MER. Detection of SMN1 to SMN2 gene conversion events and partial SMN1 gene deletions using array digital PCR. Neurogenetics (2021 Mar)

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131. Stelcer E, ..., Suchorska WM. Ionizing radiation exposure of stem cell-derived chondrocytes affects their gene and microRNA expression profiles and cytokine production. Sci Rep (2021 Apr 5)

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132. Tam WL, ..., Luyten FP. Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects. Stem Cell Res Ther (2021 Sep 25)

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133. Tsefou E, ..., Ketteler R. Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches. Biochem J (2021 Dec 10)

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134. Umek T, ..., Zain R. Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System. Nucleic Acid Ther (2021 Dec)

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135. Vila Cuenca M, ..., Orlova VV. Engineered 3D vessel-on-chip using hiPSC-derived endothelial- and vascular smooth muscle cells. Stem Cell Reports (2021 Sep 14)

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136. Virlogeux A, ..., Saudou F. Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice. Sci Adv (2021 Mar)

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137. Vogiatzis S, ..., Calistri A. Lentiviral Vectors Expressing Chimeric NEDD4 Ubiquitin Ligases: An Innovative Approach for Interfering with Alpha-Synuclein Accumulation. Cells (2021 Nov 21)

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138. Walter J, ..., Schwamborn JC. The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Rep (2021 Oct 19)

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139. Williams E, ..., Bullock AN. Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva. JCI Insight (2021 Apr 22)

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2020

140. Auslander N, ..., Ruppin E. The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases. Mol Syst Biol (2020 Dec)

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141. Badu-Mensah A, ..., Hickman JJ. Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression. Sci Rep (2020 Aug 31)

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142. Barwe SP, ..., Gopalakrishnapillai A. Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology. Mol Ther Methods Clin Dev (2020 Dec 11)

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143. Candelario KM, ..., Steindler DA. Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cells. J Comp Neurol (2020 May)

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144. Chen V, ..., Chiba-Falek O. The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations. Hum Mol Genet (2020 Nov 4)

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145. Chlebowski AC, ..., Kisby GE. Protocol for High-Throughput Screening of Neural Cell or Brain Tissue Protein Using a Dot-Blot Technique with Near-Infrared Imaging. STAR Protoc (2020 Sep 18)

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146. Colón A, ..., Hickman JJ. Differentiation of Intrafusal Fibers from Human Induced Pluripotent Stem Cells. ACS Chem Neurosci (2020 Apr 1)

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147. Dabrowska M, ..., Olejniczak M. Generation of New Isogenic Models of Huntington's Disease Using CRISPR-Cas9 Technology. Int J Mol Sci (2020 Mar 8)

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148. Das Sharma S, ..., Wyllie DJA. Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns. Mol Autism (2020 Jun 19)

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149. Depla JA, ..., Evers MM. Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain. Mol Ther Methods Clin Dev (2020 Sep 11)

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150. Dhingra A, ..., Heutink P. Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring. J Vis Exp (2020 Aug 6)

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151. Di Marco A, ..., Muñoz-Sanjuán I. Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System. Cells (2020 Apr 16)

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152. Fox LM, ..., Yamamoto A. Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. Neuron (2020 Mar 4)

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153. Franco A, ..., Dorn GW 2nd. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A. Elife (2020 Oct 19)

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154. Garcia-Diaz A, ..., Wichterle H. Standardized Reporter Systems for Purification and Imaging of Human Pluripotent Stem Cell-derived Motor Neurons and Other Cholinergic Cells. Neuroscience (2020 Dec 1)

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155. García-León JA, ..., Verfaillie CM. Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells. Nat Protoc (2020 Nov)

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156. Guo X, ..., Hickman JJ. A Human-Based Functional NMJ System for Personalized ALS Modeling and Drug Testing. Adv Ther (Weinh) (2020 Nov)

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157. Guo X, ..., Hickman JJ. Characterization of Functional Human Skeletal Myotubes and Neuromuscular Junction Derived-From the Same Induced Pluripotent Stem Cell Source. Bioengineering (Basel) (2020 Oct 22)

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158. Huang H, ..., Jin S. Signaling Molecules Regulating Pancreatic Endocrine Development from Pluripotent Stem Cell Differentiation. Int J Mol Sci (2020 Aug 15)

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159. Kerschner JL, ..., Harris A. A functional genomics approach to investigate the differentiation of iPSCs into lung epithelium at air-liquid interface. J Cell Mol Med (2020 Sep)

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160. Korecka JA, ..., Hastings ML. Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice. Mol Ther Nucleic Acids (2020 Sep 4)

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161. Lee JE, ..., Kim J. Neuroprotective Effects of Cryptotanshinone in a Direct Reprogramming Model of Parkinson's Disease. Molecules (2020 Aug 7)

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162. Li S, ..., Lu B. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Cell Rep (2020 Aug 4)

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163. Mannhardt I, ..., Eschenhagen T. Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format. Stem Cell Reports (2020 Oct 13)

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164. Ortega JA, ..., Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron (2020 Apr 8)

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165. Patel A, ..., Corneo B. Establishment and characterization of two iPSC lines derived from healthy controls. Stem Cell Res (2020 Jul 25)

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166. Patel A, ..., Hickman JJ. Myelination and Node of Ranvier Formation in a Human Motoneuron-Schwann Cell Serum-Free Coculture. ACS Chem Neurosci (2020 Sep 2)

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167. Schwartzentruber A, ..., Mortiboys H. Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons. Sci Rep (2020 Sep 23)

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168. Semmler S, ..., Vande Velde C. TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. J Biol Chem (2020 Mar 20)

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169. Sim H, ..., Kim J. Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease. Int J Mol Sci (2020 May 14)

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170. Sim H, ..., Kim J. Quantitative Proteomic Analysis of Primitive Neural Stem Cells from LRRK2 G2019S-Associated Parkinson's Disease Patient-Derived iPSCs. Life (Basel) (2020 Dec 7)

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171. Svrzikapa N, ..., Goyal J. Investigational Assay for Haplotype Phasing of the Huntingtin Gene. Mol Ther Methods Clin Dev (2020 Dec 11)

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172. Thelin EP, ..., Helmy A. Delineating Astrocytic Cytokine Responses in a Human Stem Cell Model of Neural Trauma. J Neurotrauma (2020 Jan 1)

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173. Thiruvalluvan A, ..., Kampinga HH. DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis. Mol Cell (2020 Apr 16)

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174. Tran RDH, ..., Grosberg A. The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease. J Biomech Eng (2020 Jun 1)

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175. Vázquez-Vélez GE, ..., Zoghbi HY. Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity. J Neurosci (2020 Jan 8)

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176. Voisin J, ..., Neri C. FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16(INK4a) increase. Aging Cell (2020 Nov)

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177. White JA 2nd, ..., Gunawardena S. Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease. Acta Neuropathol Commun (2020 Jul 1)

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178. Widyastuti HP, ..., Zaragoza MV. Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet (2020 Jul 22)

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179. Xu X, ..., Pouladi MA. pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model. Cell Death Dis (2020 Sep 25)

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180. Zhang W, ..., Chen JF. Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev (2020 Apr 1)

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2019

181. Abdul MM, ..., Luo Z. Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N). Stem Cell Res (2019 Dec)

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182. Aviolat H, ..., DiFiglia M. Assessing average somatic CAG repeat instability at the protein level. Sci Rep (2019 Dec 16)

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183. Babos KN, ..., Ichida JK. Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming. Cell Stem Cell (2019 Oct 3)

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184. Blackford SJI, ..., Rashid ST. Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy. Stem Cells Transl Med (2019 Feb)

[PubMed 30456803] [PMC free article] [DOI 10.1002/sctm.18-0084] [Related Cell Line IDs: NH50191] [Note: while not referenced in the text, we are aware that cell line NH50191 was used in this work.]

185. Bredenkamp N, ..., Guo G. The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells. Stem Cell Reports (2019 Jun 11)

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186. Burbulla LF, ..., Krainc D. A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson's disease. Sci Transl Med (2019 Oct 16)

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187. Cuddy LK, ..., Mazzulli JR. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. Neuron (2019 Dec 4)

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188. Custer SK, ..., Androphy EJ. Abnormal Golgi morphology and decreased COPI function in cells with low levels of SMN. Brain Res (2019 Mar 1)

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189. de Graaf MNS, ..., Orlova VV. Scalable microphysiological system to model three-dimensional blood vessels. APL Bioeng (2019 Jun)

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190. Goodman LD, ..., Bonini NM. Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nat Neurosci (2019 Jun)

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191. Hsieh CH, ..., Wang X. Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models. Cell Metab (2019 Dec 3)

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192. Hu D, ..., Qi X. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol (2019 Jun)

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193. Jiang X, ..., McMahon FJ. Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness. Mol Psychiatry (2019 Apr)

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194. Karch CM, ..., Temple S. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports (2019 Nov 12)

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195. Katt ME, ..., Searson PC. The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids Barriers CNS (2019 Jul 15)

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196. Keskin S, ..., Evers MM. AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes. Mol Ther Methods Clin Dev (2019 Dec 13)

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197. Kim H, ..., Jiang P. Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins. Stem Cell Reports (2019 May 14)

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198. Kim J, ..., Daadi MM. Non-cell autonomous mechanism of Parkinson's disease pathology caused by G2019S LRRK2 mutation in Ashkenazi Jewish patient: Single cell analysis. Brain Res (2019 Nov 1)

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199. Kulcenty K, ..., Suchorska WM. MicroRNA Profiling During Neural Differentiation of Induced Pluripotent Stem Cells. Int J Mol Sci (2019 Jul 26)

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200. Lee M, ..., Kim J. Direct Reprogramming to Human Induced Neuronal Progenitors from Fibroblasts of Familial and Sporadic Parkinson's Disease Patients. Int J Stem Cells (2019 Nov 30)

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201. Li H, ..., Tang G. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy (2019 Jan)

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202. Lynch E, ..., Suzuki M. C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells. Dis Model Mech (2019 Aug 16)

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203. Martier R, ..., Konstantinova P. Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy. Mol Ther Nucleic Acids (2019 Jun 7)

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204. Martier R, ..., Konstantinova P. Artificial MicroRNAs Targeting C9orf72 Can Reduce Accumulation of Intra-nuclear Transcripts in ALS and FTD Patients. Mol Ther Nucleic Acids (2019 Mar 1)

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205. Martier R, ..., Evers MM. Development of an AAV-Based MicroRNA Gene Therapy to Treat Machado-Joseph Disease. Mol Ther Methods Clin Dev (2019 Dec 13)

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206. Ouchi R, ..., Takebe T. Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids. Cell Metab (2019 Aug 6)

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207. Page S, ..., Al-Ahmad A. Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood-Brain Barrier is Partially Mediated Through the HIF-1 Pathway. Neuromolecular Med (2019 Dec)

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208. Ren C, ..., Liu CF. A compendious summary of Parkinson's disease patient-derived iPSCs in the first decade. Ann Transl Med (2019 Nov)

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209. Sarraf SA, ..., Pickrell AM. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep (2019 Oct 1)

[PubMed 31577952] [PMC free article] [DOI 10.1016/j.celrep.2019.08.085] [Related Cell Line IDs: ND34769, ND36091, ND40066]

210. Tagliafierro L, ..., Chiba-Falek O. Multiplication of the SNCA locus exacerbates neuronal nuclear aging. Hum Mol Genet (2019 Feb 1)

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211. Tagliafierro L, ..., Kantor B. Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models. J Vis Exp (2019 Mar 29)

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212. Tousley A, ..., Kegel-Gleason KB. Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease. J Huntingtons Dis (2019)

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213. Vethe H, ..., Ræder H. The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation. Front Endocrinol (Lausanne) (2019)

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214. Xue Y, ..., Ying M. Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons. Stem Cells Transl Med (2019 Feb)

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215. Yamada SB, ..., Gitler AD. RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nat Neurosci (2019 Sep)

[PubMed 31358992] [PMC free article] [DOI 10.1038/s41593-019-0455-7] [Related Cell Line IDs: ND50000] [Note: ND50000 is referenced in Table S3]

216. Zeitler B, ..., Zhang HS. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Nat Med (2019 Jul)

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217. Zhang W, ..., Chen JF. Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nat Commun (2019 Jun 13)

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2018

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219. Argus JP, ..., Bensinger SJ. Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling. Cell Rep (2018 Dec 4)

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220. Bell SM, ..., Mortiboys H. Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease. J Mol Biol (2018 Oct 19)

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221. Bowie LE, ..., Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proc Natl Acad Sci U S A (2018 Jul 24)

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222. Cantley W, ..., Kaplan DL. Functional and Sustainable 3D Human Neural Network Models from Pluripotent Stem Cells. ACS Biomater Sci Eng (2018 Dec 10)

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223. Connolly B, ..., Subramanian RR. SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency. J Nucleic Acids (2018)

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224. Fog CK, ..., Kirkegaard T. The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase. EBioMedicine (2018 Dec)

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225. Fontaine KA, ..., Ott M. The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein. mBio (2018 Nov 6)

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226. Ho DH, ..., Seol W. LRRK2 impairs autophagy by mediating phosphorylation of leucyl-tRNA synthetase. Cell Biochem Funct (2018 Dec)

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227. Hung CL, ..., Truant R. A patient-derived cellular model for Huntington's disease reveals phenotypes at clinically relevant CAG lengths. Mol Biol Cell (2018 Nov 15)

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228. Irmak D, ..., Vilchez D. Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations. Hum Mol Genet (2018 Dec 1)

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229. Je G, ..., Kim YS. A novel extended form of alpha-synuclein 3'UTR in the human brain. Mol Brain (2018 May 25)

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230. Joshi AU, ..., Mochly-Rosen D. Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. EMBO Mol Med (2018 Mar)

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231. Juárez-Flores DL, ..., Garrabou G. Exhaustion of mitochondrial and autophagic reserve may contribute to the development of LRRK2 (G2019S) -Parkinson's disease. J Transl Med (2018 Jun 8)

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232. Kantor B, ..., Chiba-Falek O. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. Mol Ther (2018 Nov 7)

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233. Kelley KW, ..., Rowitch DH. Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron (2018 Apr 18)

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234. Koyuncu S, ..., Vilchez D. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Nat Commun (2018 Jul 23)

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235. Luisier R, ..., Patani R. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nat Commun (2018 May 22)

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236. Ma G, ..., Mccright B. Evaluation of the differentiation status of neural stem cells based on cell morphology and the expression of Notch and Sox2. Cytotherapy (2018 Dec)

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237. Mahadevan A, ..., . Network Analysis of Developing Neural Progenitor Cells. (2018 Aug 1)

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238. McCoy MJ, ..., Ahn TH. LONGO: an R package for interactive gene length dependent analysis for neuronal identity. Bioinformatics (2018 Jul 1)

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239. McGowan H, ..., Pang ZP. hsa-let-7c miRNA Regulates Synaptic and Neuronal Function in Human Neurons. Front Synaptic Neurosci (2018)

[PubMed 30065644] [PMC free article] [DOI 10.3389/fnsyn.2018.00019] [Related Cell Line IDs: ND50026, ND50027] [Related External Line IDs: T21C1 (NHCDR line ND50026) (RMP Cell Line ID), T21C5 (NHCDR line ND50027) (RMP Cell Line ID)]

240. Milanese C, ..., Mastroberardino PG. Mitochondrial Complex I Reversible S-Nitrosation Improves Bioenergetics and Is Protective in Parkinson's Disease. Antioxid Redox Signal (2018 Jan 1)

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241. Mueller KA, ..., Sadri-Vakili G. Hippo Signaling Pathway Dysregulation in Human Huntington's Disease Brain and Neuronal Stem Cells. Sci Rep (2018 Jul 27)

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242. Nguyen M, ..., Krainc D. LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease. Proc Natl Acad Sci U S A (2018 May 22)

[PubMed 29735704] [PMC free article] [DOI 10.1073/pnas.1717590115] [Related Cell Line IDs: ND32975, ND32976]

243. Osborn TM, ..., Isacson O. Increased motor neuron resilience by small molecule compounds that regulate IGF-II expression. Neurobiol Dis (2018 Feb)

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244. Paul S, ..., Pulst SM. Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration. Nat Commun (2018 Sep 7)

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245. Pavoni S, ..., Yates F. Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes. PLoS One (2018)

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246. Pinarbasi ES, ..., Thomas PJ. Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability. Cell Rep (2018 Jun 5)

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247. Romano G, ..., Feiguin F. Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. Sci Rep (2018 Jan 29)

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248. Shaltouki A, ..., Wang X. Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models. Acta Neuropathol (2018 Oct)

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249. Stelcer E, ..., Suchorska WM. Chondrocytes differentiated from human induced pluripotent stem cells: Response to ionizing radiation. PLoS One (2018)

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250. Świtońska K, ..., Figiel M. Identification of Altered Developmental Pathways in Human Juvenile HD iPSC With 71Q and 109Q Using Transcriptome Profiling. Front Cell Neurosci (2018)

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251. Teng YD, ..., Zafonte RD. Updates on Human Neural Stem Cells: From Generation, Maintenance, and Differentiation to Applications in Spinal Cord Injury Research. Results Probl Cell Differ (2018)

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252. Victor MB, ..., Yoo AS. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nat Neurosci (2018 Mar)

[PubMed 29403030] [PMC free article] [DOI 10.1038/s41593-018-0075-7] [Related Cell Line IDs: ND30013, ND33947, ND34769, ND42235]

253. Zou L, ..., Zhan X. The Effects of Quinine on Neurophysiological Properties of Dopaminergic Neurons. Neurotox Res (2018 Jul)

[PubMed 29285614] [DOI 10.1007/s12640-017-9855-1] [Related Cell Line IDs: ND27760]

254. Zunke F, ..., Mazzulli JR. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron (2018 Jan 3)

[PubMed 29290548] [PMC free article] [DOI 10.1016/j.neuron.2017.12.012] [Related Cell Line IDs: ND34391, ND41866]

2017

255. Abernathy DG, ..., Yoo AS. MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts. Cell Stem Cell (2017 Sep 7)

[PubMed 28886366] [PMC free article] [DOI 10.1016/j.stem.2017.08.002] [Related Cell Line IDs: ND34769]

256. Al-Ahmad AJ, ..., Al-Ahmad AJ. Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells. Am J Physiol Cell Physiol (2017 Oct 1)

[PubMed 28993322] [PMC free article] [DOI 10.1152/ajpcell.00116.2017] [Related Cell Line IDs: ND41865] [Note: cell line ND41865 is referenced as "ND-41865" in the text]

257. Ando M, ..., Springer W. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener (2017 Apr 24)

[PubMed 28438176] [PMC free article] [DOI 10.1186/s13024-017-0174-z] [Related Cell Line IDs: ND40068, ND40077]

258. Bhinge A, ..., Stanton LW. Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis. Stem Cell Reports (2017 Apr 11)

[PubMed 28366453] [PMC free article] [DOI 10.1016/j.stemcr.2017.02.019] [Related Cell Line IDs: ND35662]

259. Chao MJ, ..., Lee JM. Haplotype-based stratification of Huntington's disease. Eur J Hum Genet (2017 Nov)

[PubMed 28832564] [PMC free article] [DOI 10.1038/ejhg.2017.125] [Related Cell Line IDs: ND29970, ND30013, ND30259, ND30626, ND31038, ND31551, ND33392, ND33947] [Note: cell lines are referenced in Table S6]

260. Chen MZ, ..., Hatters DM. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun (2017 Sep 7)

[PubMed 28883394] [PMC free article] [DOI 10.1038/s41467-017-00203-5] [Related Cell Line IDs: ND36997, ND36999]

261. Core JQ, ..., Grosberg A. Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations. PLoS One (2017)

[PubMed 29149195] [PMC free article] [DOI 10.1371/journal.pone.0188256] [Related Cell Line IDs: ND31845]

262. Donlin-Asp PG, ..., Rossoll W. The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly. Cell Rep (2017 Feb 14)

[PubMed 28199839] [PMC free article] [DOI 10.1016/j.celrep.2017.01.059] [Related Cell Line IDs: ND29178, ND29179]

263. Dzamko N, ..., Halliday GM. Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology. Acta Neuropathol (2017 Feb)

[PubMed 27888296] [PMC free article] [DOI 10.1007/s00401-016-1648-8] [Related Cell Line IDs: ND38530]

264. Hall CE, ..., Patani R. Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Rep (2017 May 30)

[PubMed 28564594] [PMC free article] [DOI 10.1016/j.celrep.2017.05.024] [Related Cell Line IDs: ND41866]

265. Heman-Ackah SM, ..., Wood MJA. Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons. Hum Mol Genet (2017 Nov 15)

[PubMed 28973645] [PMC free article] [DOI 10.1093/hmg/ddx331] [Related External Line IDs: NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)]

266. Konrad C, ..., Manfredi G. Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients. Mol Neurodegener (2017 Oct 24)

[PubMed 29065921] [PMC free article] [DOI 10.1186/s13024-017-0217-5] [Related Cell Line IDs: ND29149, ND29422, ND29774, ND39022, ND39023]

267. Lavado A, ..., Hickman JJ. Evaluation of Holistic Treatment for ALS Reveals Possible Mechanism and Therapeutic Potential. Int J Pharm Pharm Res (2017 Dec)

[PubMed 30637316] [PMC free article] [Related Cell Line IDs: ND39032, ND41865]

268. Maiuri T, ..., Truant R. Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex. Hum Mol Genet (2017 Jan 15)

[PubMed 28017939] [DOI 10.1093/hmg/ddw395] [Related Cell Line IDs: ND30013, ND30014, ND30626, ND33391]

269. Malloy KE, ..., Daadi MM. Magnetic Resonance Imaging-Guided Delivery of Neural Stem Cells into the Basal Ganglia of Nonhuman Primates Reveals a Pulsatile Mode of Cell Dispersion. Stem Cells Transl Med (2017 Mar)

[PubMed 28297573] [PMC free article] [DOI 10.5966/sctm.2016-0269] [Related Cell Line IDs: ND29802]

270. Monteys AM, ..., Davidson BL. CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo. Mol Ther (2017 Jan 4)

[PubMed 28129107] [PMC free article] [DOI 10.1016/j.ymthe.2016.11.010] [Related Cell Line IDs: ND31551, ND33392]

271. Oleksiewicz U, ..., Wiznerowicz M. TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes. Stem Cell Reports (2017 Dec 12)

[PubMed 29198826] [PMC free article] [DOI 10.1016/j.stemcr.2017.10.031] [Related Cell Line IDs: ND41658]

272. Pandya H, ..., Park JK. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells. Nat Neurosci (2017 May)

[PubMed 28253233] [PMC free article] [DOI 10.1038/nn.4534] [Related External Line IDs: NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)]

273. Patel R, ..., Al-Ahmad AJ. Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality. J Neurochem (2017 Jul)

[PubMed 28397247] [DOI 10.1111/jnc.14040] [Related Google Scholar Queries: "coriell" "ninds" "ipsc" OR "fibroblast", "nhcdr", "repository" "ninds" "ipsc" OR "fibroblast"]

274. Quinti L, ..., Kazantsev AG. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proc Natl Acad Sci U S A (2017 Jun 6)

[PubMed 28533375] [PMC free article] [DOI 10.1073/pnas.1614943114] [Related Cell Line IDs: ND38548, ND38551, ND38554]

275. Schwab AJ, ..., Ebert AD. Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons. Stem Cell Reports (2017 Dec 12)

[PubMed 29129681] [PMC free article] [DOI 10.1016/j.stemcr.2017.10.010] [Related Cell Line IDs: ND35367, ND40018, ND40019]

276. Son MY, ..., Kim J. Distinctive genomic signature of neural and intestinal organoids from familial Parkinson's disease patient-derived induced pluripotent stem cells. Neuropathol Appl Neurobiol (2017 Dec)

[PubMed 28235153] [DOI 10.1111/nan.12396] [Related Cell Line IDs: ND29492, ND33879, ND38262]

277. Szlachcic WJ, ..., Figiel M. The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function. Front Mol Neurosci (2017)

[PubMed 28848389] [PMC free article] [DOI 10.3389/fnmol.2017.00253] [Related Cell Line IDs: ND42224, ND42228, ND42245]

278. Tagliafierro L, ..., Chiba-Falek O. Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies. Alzheimers Dement (2017 Nov)

[PubMed 28431219] [PMC free article] [DOI 10.1016/j.jalz.2017.03.001] [Related Cell Line IDs: ND34391]

279. Takata K, ..., Ginhoux F. Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function. Immunity (2017 Jul 18)

[PubMed 28723550] [DOI 10.1016/j.immuni.2017.06.017] [Related Cell Line IDs: ND36997]

280. Teves JMY, ..., Madhavan L. Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy. Front Neurosci (2017)

[PubMed 29379409] [PMC free article] [DOI 10.3389/fnins.2017.00737] [Related Cell Line IDs: ND32973]

281. Vasquez V, ..., Hegde ML. Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease. J Alzheimers Dis (2017)

[PubMed 28731447] [PMC free article] [DOI 10.3233/JAD-170342] [Related Cell Line IDs: ND34391]

282. Verma M, ..., Chu CT. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants. J Neurosci (2017 Nov 15)

[PubMed 29038245] [PMC free article] [DOI 10.1523/JNEUROSCI.3791-16.2017] [Related Cell Line IDs: ND32975, ND33879, ND34769]

283. Wang L, ..., Liu GH. CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs. Protein Cell (2017 May)

[PubMed 28401346] [PMC free article] [DOI 10.1007/s13238-017-0397-3] [Related Cell Line IDs: ND29149, ND29563]

284. Xu X, ..., Pouladi MA. Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells. Stem Cell Reports (2017 Mar 14)

[PubMed 28238795] [PMC free article] [DOI 10.1016/j.stemcr.2017.01.022] [Related Cell Line IDs: ND36997, ND36999]

285. Zhong P, ..., Feng J. Dopamine Induces Oscillatory Activities in Human Midbrain Neurons with Parkin Mutations. Cell Rep (2017 May 2)

[PubMed 28467897] [PMC free article] [DOI 10.1016/j.celrep.2017.04.023] [Related Cell Line IDs: ND30171]

2016

286. Borgs L, ..., Nguyen L. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep (2016 Sep 19)

[PubMed 27640816] [PMC free article] [DOI 10.1038/srep33377] [Related Cell Line IDs: ND29370]

287. Cho KJ, ..., Hancock JF. Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane. Mol Cell Biol (2016 Jan 15)

[PubMed 26572827] [PMC free article] [DOI 10.1128/MCB.00719-15] [Related Cell Line IDs: ND29510]

288. Heman-Ackah SM, ..., Wood MJ. Precision Modulation of Neurodegenerative Disease-Related Gene Expression in Human iPSC-Derived Neurons. Sci Rep (2016 Jun 24)

[PubMed 27341390] [PMC free article] [DOI 10.1038/srep28420] [Related External Line IDs: NCRM-1 (NHCDR line ND50028) (RMP Cell Line ID), NCRM-5 (NHCDR line ND50031) (RMP Cell Line ID)]

289. Hsieh CH, ..., Wang X. Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease. Cell Stem Cell (2016 Dec 1)

[PubMed 27618216] [PMC free article] [DOI 10.1016/j.stem.2016.08.002] [Related Cell Line IDs: ND39896, ND41866]

290. Lin L, ..., Stanton LW. Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients. Cell Rep (2016 Jun 14)

[PubMed 27264186] [DOI 10.1016/j.celrep.2016.05.022] [Related Cell Line IDs: ND34391, ND35367, ND38477, ND39896, ND40018]

291. Liu ML, ..., Zhang CL. Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients. Cell Rep (2016 Jan 5)

[PubMed 26725112] [PMC free article] [DOI 10.1016/j.celrep.2015.12.018] [Related Cell Line IDs: ND29563, ND39027, ND40077]

292. Mazzulli JR, ..., Krainc D. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. J Neurosci (2016 Jul 20)

[PubMed 27445146] [PMC free article] [DOI 10.1523/JNEUROSCI.0628-16.2016] [Related Cell Line IDs: ND39896]

293. Mungenast AE, ..., Tsai LH. Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells. Mol Cell Neurosci (2016 Jun)

[PubMed 26657644] [PMC free article] [DOI 10.1016/j.mcn.2015.11.010] [Related Cell Line IDs: ND40076]

294. Narayan M, ..., Jinwal UK. Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts. Biomark Med (2016 May)

[PubMed 27141953] [DOI 10.2217/bmm-2016-0025] [Related Cell Line IDs: ND29178, ND29194, ND29422, ND29509, ND29774, ND32947, ND34769, ND36091, ND38530]

295. Noormohammadi A, ..., Vilchez D. Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan. Nat Commun (2016 Nov 28)

[PubMed 27892468] [PMC free article] [DOI 10.1038/ncomms13649] [Related Cell Line IDs: ND30014, ND33392, ND36997, ND36998, ND36999, ND41656, ND42229, ND42242]

296. Pryde KR, ..., Schapira AH. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol (2016 Apr 25)

[PubMed 27091447] [PMC free article] [DOI 10.1083/jcb.201509003] [Related Cell Line IDs: ND40066]

297. Raja WK, ..., Tsai LH. Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. PLoS One (2016)

[PubMed 27622770] [PMC free article] [DOI 10.1371/journal.pone.0161969] [Related Cell Line IDs: ND34732]

298. Sepe S, ..., Mastroberardino PG. Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease. Cell Rep (2016 May 31)

[PubMed 27210754] [PMC free article] [DOI 10.1016/j.celrep.2016.04.071] [Related Cell Line IDs: ND32975, ND32976, ND33879]

299. Tousley A, ..., Kegel-Gleason KB. Induced Pluripotent Stem Cells in Huntington's Disease Research: Progress and Opportunity. J Huntingtons Dis (2016 Jun 28)

[PubMed 27372054] [PMC free article] [DOI 10.3233/JHD-160199] [Related Cell Line IDs: ND41658, ND42223, ND42224, ND42228, ND42230, ND42245]

300. Urbanek MO, ..., Krzyzosiak WJ. RNA FISH for detecting expanded repeats in human diseases. Methods (2016 Apr 1)

[PubMed 26615955] [DOI 10.1016/j.ymeth.2015.11.017] [Related Cell Line IDs: ND41657, ND41658]

301. Vazquez-Arango P, ..., O'Reilly D. Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease. Nucleic Acids Res (2016 Dec 15)

[PubMed 27536002] [PMC free article] [DOI 10.1093/nar/gkw711] [Related Cell Line IDs: ND30625]

302. Zhou Q, ..., Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun (2016 Jan 12)

[PubMed 26755131] [PMC free article] [DOI 10.1038/ncomms10332] [Related Google Scholar Queries: "coriell" "ninds" "ipsc" OR "fibroblast", "repository" "ninds" "ipsc" OR "fibroblast"]

2015

303. Du ZW, ..., Zhang SC. Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells. Nat Commun (2015 Mar 25)

[PubMed 25806427] [PMC free article] [DOI 10.1038/ncomms7626] [Related Cell Line IDs: ND29149, ND35671]

304. Ho DH, ..., Seol W. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain (2015 Sep 18)

[PubMed 26384650] [PMC free article] [DOI 10.1186/s13041-015-0145-7] [Related Cell Line IDs: ND29492]

305. Iovino M, ..., Spillantini MG. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations. Brain (2015 Nov)

[PubMed 26220942] [PMC free article] [DOI 10.1093/brain/awv222] [Related Cell Line IDs: ND40076]

306. Khan TK, ..., Alkon DL. PKCε deficits in Alzheimer's disease brains and skin fibroblasts. J Alzheimers Dis (2015)

[PubMed 25125477] [DOI 10.3233/JAD-141221] [Related Cell Line IDs: ND27760, ND31618, ND34265]

307. Ring KL, ..., Ellerby LM. Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington's Disease Neural Stem Cells. Stem Cell Reports (2015 Dec 8)

[PubMed 26651603] [PMC free article] [DOI 10.1016/j.stemcr.2015.11.005] [Related Cell Line IDs: ND41656, ND42222]

308. Schwab AJ, ..., Ebert AD. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports (2015 Dec 8)

[PubMed 26651604] [PMC free article] [DOI 10.1016/j.stemcr.2015.11.004] [Related Cell Line IDs: ND34391, ND35367, ND40018, ND40019]

309. Su YC, ..., Qi X. Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy. Biochim Biophys Acta (2015 Jan)

[PubMed 25446991] [PMC free article] [DOI 10.1016/j.bbadis.2014.11.009] [Related Cell Line IDs: ND29802, ND33879]

310. Szlachcic WJ, ..., Figiel M. Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway. Dis Model Mech (2015 Sep)

[PubMed 26092128] [PMC free article] [DOI 10.1242/dmm.019406] [Related Cell Line IDs: ND41658, ND42223, ND42224, ND42228, ND42230, ND42245]

311. Takahashi M, ..., Hohjoh H. Normalization of Overexpressed α-Synuclein Causing Parkinson's Disease By a Moderate Gene Silencing With RNA Interference. Mol Ther Nucleic Acids (2015 May 12)

[PubMed 25965551] [DOI 10.1038/mtna.2015.14] [Related Cell Line IDs: ND27760, ND29510]

312. York AG, ..., Bensinger SJ. Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. Cell (2015 Dec 17)

[PubMed 26686653] [PMC free article] [DOI 10.1016/j.cell.2015.11.045] [Related Cell Line IDs: ND38530]

2014

313. Bellani S, ..., Chieregatti E. GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein. Cell Death Differ (2014 Dec)

[PubMed 25124556] [PMC free article] [DOI 10.1038/cdd.2014.111] [Related Cell Line IDs: ND27760]

314. Chen H, ..., Zhang SC. Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons. Cell Stem Cell (2014 Jun 5)

[PubMed 24704493] [PMC free article] [DOI 10.1016/j.stem.2014.02.004] [Related Cell Line IDs: ND29149, ND35671]

315. Lu HF, ..., Wan AC. A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells. Biomaterials (2014 Mar)

[PubMed 24411336] [DOI 10.1016/j.biomaterials.2013.12.050] [Related Cell Line IDs: ND30116]

316. Sagal J, ..., Ying M. Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons. Stem Cells Transl Med (2014 Aug)

[PubMed 24904172] [PMC free article] [DOI 10.5966/sctm.2013-0213] [Related Cell Line IDs: ND27760]

317. Sanders LH, ..., Schüle B. LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. Neurobiol Dis (2014 Feb)

[PubMed 24148854] [PMC free article] [DOI 10.1016/j.nbd.2013.10.013] [Related Cell Line IDs: ND34393, ND34394, ND35367]

318. Skibinski G, ..., Finkbeiner S. Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. J Neurosci (2014 Jan 8)

[PubMed 24403142] [PMC free article] [DOI 10.1523/JNEUROSCI.2712-13.2014] [Related Cell Line IDs: ND35367]

2013

319. Allen GF, ..., Ganley IG. Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep (2013 Dec)

[PubMed 24176932] [PMC free article] [DOI 10.1038/embor.2013.168] [Related Cell Line IDs: ND29543]

320. Liu ML, ..., Zhang CL. Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. Nat Commun (2013)

[PubMed 23873306] [PMC free article] [DOI 10.1038/ncomms3183] [Related Cell Line IDs: ND29563]

321. Lu J, ..., Zhang SC. Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep (2013 May 30)

[PubMed 23643533] [PMC free article] [DOI 10.1016/j.celrep.2013.04.004] [Related Cell Line IDs: ND32947]

2012

322. Cooper O, ..., Isacson O. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Sci Transl Med (2012 Jul 4)

[PubMed 22764206] [PMC free article] [DOI 10.1126/scitranslmed.3003985] [Related Cell Line IDs: ND29492, ND29802, ND30244, ND32944]

323. Egawa N, ..., Inoue H. Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012 Aug 1)

[PubMed 22855461] [DOI 10.1126/scitranslmed.3004052] [Related Cell Line IDs: ND32947]

324. Wray S, ..., Hardy J. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLoS One (2012)

[PubMed 22952635] [PMC free article] [DOI 10.1371/journal.pone.0043099] [Related Google Scholar Queries: "coriell" "ninds" "ipsc" OR "fibroblast", "repository" "ninds" "ipsc" OR "fibroblast"]

325. Yagi T, ..., Suzuki N. Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. PLoS One (2012)

[PubMed 22848530] [PMC free article] [DOI 10.1371/journal.pone.0041572] [Related Cell Line IDs: ND27760]

2011

326. Devine MJ, ..., Kunath T. Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus. Nat Commun (2011 Aug 23)

[PubMed 21863007] [PMC free article] [DOI 10.1038/ncomms1453] [Related Cell Line IDs: ND27760]

327. Serviddio G, ..., Vendemiale G. Principles and therapeutic relevance for targeting mitochondria in aging and neurodegenerative diseases. Curr Pharm Des (2011)

[PubMed 21718251] [DOI 10.2174/138161211796904740] [Related RUIDs: NN0004337, NN0004344]

Note

These publications were found using a combination of automated Google Scholar searches and manual review. When possible, we show specific identifiers, such as NHCDR cell line IDs, that were cited in the text. In some cases, when no specific identifiers were found, we instead show NHCDR-related terms. The terms are sometimes provided in the form of Google Scholar queries that yield the publication, such as "repository" "ninds" "ipsc" OR "fibroblast" (you can try this search here). If you have access to the full text of the publication (we provide links when possible), you can search the text for the IDs and/or terms to determine exactly how NHCDR resources were used in the publication.

We are grateful to SerpApi for providing critical data mining services used to produce this list.

This collection was formerly maintained at the Coriell Repository. While some papers may still reference Coriell, the cell line resources they used are now maintained at the NHCDR.