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Catalog of the NINDS Human Cell and Data Repository


We are grateful to SerpApi for providing some of the data mining services used to produce this list.


1. Fukusumi H, ..., Kanemura Y. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio (2021 Feb)

[PubMed] [PMC free article] [DOI 10.1002/2211-5463.13060] [Related Cell Line IDs: ND27760]

2. Stabley DL, ..., Butchbach MER. Detection of SMN1 to SMN2 gene conversion events and partial SMN1 gene deletions using array digital PCR. Neurogenetics (2021 Mar)

[PubMed] [DOI 10.1007/s10048-020-00630-5] [Related Cell Line IDs: ND29563, ND32947, ND39027, ND40077, ND41003]


3. Das Sharma S, ..., Wyllie DJA. Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns. Mol Autism (2020 Jun 19)

[PubMed] [PMC free article] [DOI 10.1186/s13229-020-00351-4] [Related Cell Line IDs: ND30625]

4. Franco A, ..., Dorn GW 2nd. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A. Elife (2020 Oct 19)

[PubMed] [PMC free article] [DOI 10.7554/eLife.61119] [Related Cell Line IDs: ND29178, ND29510, ND34769, ND34770, ND36320, ND38530]

5. Li S, ..., Lu B. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Cell Rep (2020 Aug 4)

[PubMed] [PMC free article] [DOI 10.1016/j.celrep.2020.107989] [Related Cell Line IDs: ND29510, ND29971]

6. Schwartzentruber A, ..., Mortiboys H. Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons. Sci Rep (2020 Sep 23)

[PubMed] [PMC free article] [DOI 10.1038/s41598-020-72345-4] [Related Cell Line IDs: ND29510, ND30171, ND31618, ND40067, ND40078]

7. Sim H, ..., Kim J. Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease. Int J Mol Sci (2020 May 14)

[PubMed] [PMC free article] [DOI 10.3390/ijms21103455] [Related Cell Line IDs: ND29492, ND33879, ND38262]

8. Svrzikapa N, ..., Goyal J. Investigational Assay for Haplotype Phasing of the Huntingtin Gene. Mol Ther Methods Clin Dev (2020 Dec 11)

[PubMed] [PMC free article] [DOI 10.1016/j.omtm.2020.09.003] [Related Cell Line IDs: ND30259]

9. Tran RDH, ..., Grosberg A. The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease. J Biomech Eng (2020 Jun 1)

[PubMed] [PMC free article] [DOI 10.1115/1.4044091] [Related Cell Line IDs: ND31845]

10. Widyastuti HP, ..., Zaragoza MV. Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis. BMC Med Genet (2020 Jul 22)

[PubMed] [PMC free article] [DOI 10.1186/s12881-020-01088-w] [Related Cell Line IDs: ND31845]


11. Babos KN, ..., Ichida JK. Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming. Cell Stem Cell (2019 Oct 3)

[PubMed] [PMC free article] [DOI 10.1016/j.stem.2019.08.005] [Related Cell Line IDs: ND39023]

12. Blackford SJI, ..., Rashid ST. Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy. Stem Cells Transl Med (2019 Feb)

[PubMed] [PMC free article] [DOI 10.1002/sctm.18-0084]

13. Bredenkamp N, ..., Guo G. The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells. Stem Cell Reports (2019 Jun 11)

[PubMed] [PMC free article] [DOI 10.1016/j.stemcr.2019.03.014]

14. Custer SK, ..., Androphy EJ. Abnormal Golgi morphology and decreased COPI function in cells with low levels of SMN. Brain Res (2019 Mar 1)

[PubMed] [PMC free article] [DOI 10.1016/j.brainres.2018.11.005] [Related Cell Line IDs: ND29563]

15. Goodman LD, ..., Bonini NM. Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nat Neurosci (2019 Jun)

[PubMed] [PMC free article] [DOI 10.1038/s41593-019-0396-1]

16. Hsieh CH, ..., Wang X. Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models. Cell Metab (2019 Dec 3)

[PubMed] [PMC free article] [DOI 10.1016/j.cmet.2019.08.023] [Related Cell Line IDs: ND39896, ND41864, ND50050, ND50085]

17. Hu D, ..., Qi X. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol (2019 Jun)

[PubMed] [PMC free article] [DOI 10.1007/s00401-019-01993-2]

18. Katt ME, ..., Searson PC. The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids Barriers CNS (2019 Jul 15)

[PubMed] [PMC free article] [DOI 10.1186/s12987-019-0139-4]

19. Kim J, ..., Daadi MM. Non-cell autonomous mechanism of Parkinson's disease pathology caused by G2019S LRRK2 mutation in Ashkenazi Jewish patient: Single cell analysis. Brain Res (2019 Nov 1)

[PubMed] [PMC free article] [DOI 10.1016/j.brainres.2019.146342] [Related Cell Line IDs: ND29802]

20. Li H, ..., Tang G. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy (2019 Jan)

[PubMed] [PMC free article] [DOI 10.1080/15548627.2018.1509818] [Related Cell Line IDs: ND30364]

21. Lynch E, ..., Suzuki M. C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells. Dis Model Mech (2019 Aug 16)

[PubMed] [PMC free article] [DOI 10.1242/dmm.039552]

22. Martier R, ..., Konstantinova P. Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy. Mol Ther Nucleic Acids (2019 Jun 7)

[PubMed] [PMC free article] [DOI 10.1016/j.omtn.2019.02.001] [Related Cell Line IDs: ND42245, ND42765]

23. Ouchi R, ..., Takebe T. Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids. Cell Metab (2019 Aug 6)

[PubMed] [PMC free article] [DOI 10.1016/j.cmet.2019.05.007] [Related Cell Line IDs: ND50022, ND50023]

24. Surendran H, ..., Pal R. Differentiating Human Induced Pluripotent Stem Cells (iPSCs) Into Lung Epithelial Cells. Curr Protoc Stem Cell Biol (2019 Jun)

[PubMed] [DOI 10.1002/cpsc.86]

25. Xue Y, ..., Ying M. Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons. Stem Cells Transl Med (2019 Feb)

[PubMed] [PMC free article] [DOI 10.1002/sctm.18-0036] [Related Cell Line IDs: ND27760]

26. Yamada SB, ..., Gitler AD. RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nat Neurosci (2019 Sep)

[PubMed] [PMC free article] [DOI 10.1038/s41593-019-0455-7]

27. Zeitler B, ..., Zhang HS. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Nat Med (2019 Jul)

[PubMed] [DOI 10.1038/s41591-019-0478-3] [Related Cell Line IDs: ND30259]

28. Zhang W, ..., Chen JF. Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nat Commun (2019 Jun 13)

[PubMed] [PMC free article] [DOI 10.1038/s41467-019-10497-2]


29. Bowie LE, ..., Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proc Natl Acad Sci U S A (2018 Jul 24)

[PubMed] [PMC free article] [DOI 10.1073/pnas.1801772115] [Related Cell Line IDs: ND30014]

30. Fontaine KA, ..., Ott M. The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein. mBio (2018 Nov 6)

[PubMed] [PMC free article] [DOI 10.1128/mBio.02126-18] [Related Cell Line IDs: ND29971, ND30625, ND31845]

31. Ho DH, ..., Seol W. LRRK2 impairs autophagy by mediating phosphorylation of leucyl-tRNA synthetase. Cell Biochem Funct (2018 Dec)

[PubMed] [DOI 10.1002/cbf.3364] [Related Cell Line IDs: ND29492]

32. Hung CL, ..., Truant R. A patient-derived cellular model for Huntington's disease reveals phenotypes at clinically relevant CAG lengths. Mol Biol Cell (2018 Nov 15)

[PubMed] [PMC free article] [DOI 10.1091/mbc.E18-09-0590] [Related Cell Line IDs: ND30013, ND30014]

33. Joshi AU, ..., Mochly-Rosen D. Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. EMBO Mol Med (2018 Mar)

[PubMed] [PMC free article] [DOI 10.15252/emmm.201708166] [Related Cell Line IDs: ND29509, ND32969]

34. Kantor B, ..., Chiba-Falek O. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. Mol Ther (2018 Nov 7)

[PubMed] [PMC free article] [DOI 10.1016/j.ymthe.2018.08.019] [Related Cell Line IDs: ND34391]

35. Koyuncu S, ..., Vilchez D. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Nat Commun (2018 Jul 23)

[PubMed] [PMC free article] [DOI 10.1038/s41467-018-05320-3] [Related Cell Line IDs: ND30014, ND33392, ND36997, ND36999, ND41656, ND42230, ND42242]

36. Ma G, ..., Mccright B. Evaluation of the differentiation status of neural stem cells based on cell morphology and the expression of Notch and Sox2. Cytotherapy (2018 Dec)

[PubMed] [DOI 10.1016/j.jcyt.2018.10.001]

37. McGowan H, ..., Pang ZP. hsa-let-7c miRNA Regulates Synaptic and Neuronal Function in Human Neurons. Front Synaptic Neurosci (2018)

[PubMed] [PMC free article] [DOI 10.3389/fnsyn.2018.00019] [Related Cell Line IDs: ND50026, ND50027]

38. Shaltouki A, ..., Wang X. Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models. Acta Neuropathol (2018 Oct)

[PubMed] [PMC free article] [DOI 10.1007/s00401-018-1873-4] [Related Cell Line IDs: ND34391, ND41864, ND50049]

39. Shi Y, ..., Ichida JK. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nat Med (2018 Mar)

[PubMed] [PMC free article] [DOI 10.1038/nm.4490]

40. Zou L, ..., Zhan X. The Effects of Quinine on Neurophysiological Properties of Dopaminergic Neurons. Neurotox Res (2018 Jul)

[PubMed] [DOI 10.1007/s12640-017-9855-1] [Related Cell Line IDs: ND27760]


41. Al-Ahmad AJ, ..., Al-Ahmad AJ. Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells. Am J Physiol Cell Physiol (2017 Oct 1)

[PubMed] [PMC free article] [DOI 10.1152/ajpcell.00116.2017]

42. Chao MJ, ..., Lee JM. Haplotype-based stratification of Huntington's disease. Eur J Hum Genet (2017 Nov)

[PubMed] [PMC free article] [DOI 10.1038/ejhg.2017.125]

43. Core JQ, ..., Grosberg A. Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations. PLoS One (2017)

[PubMed] [PMC free article] [DOI 10.1371/journal.pone.0188256] [Related Cell Line IDs: ND31845]

44. Donlin-Asp PG, ..., Rossoll W. The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly. Cell Rep (2017 Feb 14)

[PubMed] [PMC free article] [DOI 10.1016/j.celrep.2017.01.059] [Related Cell Line IDs: ND29178, ND29179]

45. Konrad C, ..., Manfredi G. Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients. Mol Neurodegener (2017 Oct 24)

[PubMed] [PMC free article] [DOI 10.1186/s13024-017-0217-5] [Related Cell Line IDs: ND29149, ND29422, ND29774, ND39022, ND39023]

46. Maiuri T, ..., Truant R. Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex. Hum Mol Genet (2017 Jan 15)

[PubMed] [DOI 10.1093/hmg/ddw395] [Related Cell Line IDs: ND30013, ND30014, ND30626, ND33391]

47. Malloy KE, ..., Daadi MM. Magnetic Resonance Imaging-Guided Delivery of Neural Stem Cells into the Basal Ganglia of Nonhuman Primates Reveals a Pulsatile Mode of Cell Dispersion. Stem Cells Transl Med (2017 Mar)

[PubMed] [PMC free article] [DOI 10.5966/sctm.2016-0269] [Related Cell Line IDs: ND29802]

48. Monteys AM, ..., Davidson BL. CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo. Mol Ther (2017 Jan 4)

[PubMed] [PMC free article] [DOI 10.1016/j.ymthe.2016.11.010] [Related Cell Line IDs: ND31551, ND33392]

49. Son MY, ..., Kim J. Distinctive genomic signature of neural and intestinal organoids from familial Parkinson's disease patient-derived induced pluripotent stem cells. Neuropathol Appl Neurobiol (2017 Dec)

[PubMed] [DOI 10.1111/nan.12396] [Related Cell Line IDs: ND29492, ND33879, ND38262]

50. Tagliafierro L, ..., Chiba-Falek O. Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies. Alzheimers Dement (2017 Nov)

[PubMed] [PMC free article] [DOI 10.1016/j.jalz.2017.03.001] [Related Cell Line IDs: ND34391]

51. Teves JMY, ..., Madhavan L. Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy. Front Neurosci (2017)

[PubMed] [PMC free article] [DOI 10.3389/fnins.2017.00737] [Related Cell Line IDs: ND32973]

52. Wang L, ..., Liu GH. CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs. Protein Cell (2017 May)

[PubMed] [PMC free article] [DOI 10.1007/s13238-017-0397-3] [Related Cell Line IDs: ND29149, ND29563]

53. Zhong P, ..., Feng J. Dopamine Induces Oscillatory Activities in Human Midbrain Neurons with Parkin Mutations. Cell Rep (2017 May 2)

[PubMed] [PMC free article] [DOI 10.1016/j.celrep.2017.04.023] [Related Cell Line IDs: ND30171]


54. Borgs L, ..., Nguyen L. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep (2016 Sep 19)

[PubMed] [PMC free article] [DOI 10.1038/srep33377] [Related Cell Line IDs: ND29370]

55. Cho KJ, ..., Hancock JF. Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane. Mol Cell Biol (2016 Jan 15)

[PubMed] [PMC free article] [DOI 10.1128/MCB.00719-15] [Related Cell Line IDs: ND29510]

56. Heman-Ackah SM, ..., Wood MJ. Precision Modulation of Neurodegenerative Disease-Related Gene Expression in Human iPSC-Derived Neurons. Sci Rep (2016 Jun 24)

[PubMed] [PMC free article] [DOI 10.1038/srep28420]

57. Hsieh CH, ..., Wang X. Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease. Cell Stem Cell (2016 Dec 1)

[PubMed] [PMC free article] [DOI 10.1016/j.stem.2016.08.002] [Related Cell Line IDs: ND39896, ND41866]

58. Liu ML, ..., Zhang CL. Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients. Cell Rep (2016 Jan 5)

[PubMed] [PMC free article] [DOI 10.1016/j.celrep.2015.12.018] [Related Cell Line IDs: ND29563, ND39027, ND40077]

59. Narayan M, ..., Jinwal UK. Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts. Biomark Med (2016 May)

[PubMed] [DOI 10.2217/bmm-2016-0025] [Related Cell Line IDs: ND29178, ND29194, ND29422, ND29509, ND29774, ND32947, ND34769, ND36091, ND38530]

60. Noormohammadi A, ..., Vilchez D. Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan. Nat Commun (2016 Nov 28)

[PubMed] [PMC free article] [DOI 10.1038/ncomms13649] [Related Cell Line IDs: ND30014, ND33392, ND36997, ND36998, ND36999, ND41656, ND42229, ND42242]

61. Vazquez-Arango P, ..., O'Reilly D. Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease. Nucleic Acids Res (2016 Dec 15)

[PubMed] [PMC free article] [DOI 10.1093/nar/gkw711] [Related Cell Line IDs: ND30625]


62. Du ZW, ..., Zhang SC. Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells. Nat Commun (2015 Mar 25)

[PubMed] [PMC free article] [DOI 10.1038/ncomms7626] [Related Cell Line IDs: ND29149, ND35671]

63. Ho DH, ..., Seol W. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain (2015 Sep 18)

[PubMed] [PMC free article] [DOI 10.1186/s13041-015-0145-7] [Related Cell Line IDs: ND29492]

64. Khan TK, ..., Alkon DL. PKCε deficits in Alzheimer's disease brains and skin fibroblasts. J Alzheimers Dis (2015)

[PubMed] [DOI 10.3233/JAD-141221] [Related Cell Line IDs: ND27760, ND31618, ND34265]

65. Su YC, ..., Qi X. Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy. Biochim Biophys Acta (2015 Jan)

[PubMed] [PMC free article] [DOI 10.1016/j.bbadis.2014.11.009] [Related Cell Line IDs: ND29802, ND33879]

66. Takahashi M, ..., Hohjoh H. Normalization of Overexpressed α-Synuclein Causing Parkinson's Disease By a Moderate Gene Silencing With RNA Interference. Mol Ther Nucleic Acids (2015 May 12)

[PubMed] [DOI 10.1038/mtna.2015.14] [Related Cell Line IDs: ND27760, ND29510]


67. Bellani S, ..., Chieregatti E. GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein. Cell Death Differ (2014 Dec)

[PubMed] [PMC free article] [DOI 10.1038/cdd.2014.111] [Related Cell Line IDs: ND27760]

68. Chen H, ..., Zhang SC. Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons. Cell Stem Cell (2014 Jun 5)

[PubMed] [PMC free article] [DOI 10.1016/j.stem.2014.02.004] [Related Cell Line IDs: ND29149, ND35671]

69. Lu HF, ..., Wan AC. A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells. Biomaterials (2014 Mar)

[PubMed] [DOI 10.1016/j.biomaterials.2013.12.050] [Related Cell Line IDs: ND30116]

70. Sagal J, ..., Ying M. Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons. Stem Cells Transl Med (2014 Aug)

[PubMed] [PMC free article] [DOI 10.5966/sctm.2013-0213] [Related Cell Line IDs: ND27760]


71. Allen GF, ..., Ganley IG. Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep (2013 Dec)

[PubMed] [PMC free article] [DOI 10.1038/embor.2013.168] [Related Cell Line IDs: ND29543]

72. Liu ML, ..., Zhang CL. Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. Nat Commun (2013)

[PubMed] [PMC free article] [DOI 10.1038/ncomms3183] [Related Cell Line IDs: ND29563]

73. Lu J, ..., Zhang SC. Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep (2013 May 30)

[PubMed] [PMC free article] [DOI 10.1016/j.celrep.2013.04.004] [Related Cell Line IDs: ND32947]


74. Cooper O, ..., Isacson O. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Sci Transl Med (2012 Jul 4)

[PubMed] [PMC free article] [DOI 10.1126/scitranslmed.3003985] [Related Cell Line IDs: ND29492, ND29802, ND30244, ND32944]

75. Yagi T, ..., Suzuki N. Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research. PLoS One (2012)

[PubMed] [PMC free article] [DOI 10.1371/journal.pone.0041572] [Related Cell Line IDs: ND27760]


76. Devine MJ, ..., Kunath T. Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus. Nat Commun (2011 Aug 23)

[PubMed] [PMC free article] [DOI 10.1038/ncomms1453] [Related Cell Line IDs: ND27760]

77. Abdul MM, ..., Luo Z. Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N). Stem Cell Res (2019 Dec)

[PubMed] [DOI 10.1016/j.scr.2019.101607]

78. Abernathy DG, ..., Yoo AS. MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts. Cell Stem Cell (2017 Sep 7)

[PubMed] [PMC free article] [DOI 10.1016/j.stem.2017.08.002]

79. Ando M, ..., Springer W. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener (2017 Apr 24)

[PubMed] [PMC free article] [DOI 10.1186/s13024-017-0174-z]

80. Argus JP, ..., Bensinger SJ. Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling. Cell Rep (2018 Dec 4)

[PubMed] [PMC free article] [DOI 10.1016/j.celrep.2018.11.041]

81. Aviolat H, ..., DiFiglia M. Assessing average somatic CAG repeat instability at the protein level. Sci Rep (2019 Dec 16)

[PubMed] [PMC free article] [DOI 10.1038/s41598-019-55202-x]

82. Badu-Mensah A, ..., Hickman JJ. Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression. Sci Rep (2020 Aug 31)

[PubMed] [PMC free article] [DOI 10.1038/s41598-020-70510-3]

83. Bell SM, ..., Mortiboys H. Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease. J Mol Biol (2018 Oct 19)

[PubMed] [PMC free article] [DOI 10.1016/j.jmb.2018.08.019]

84. Bhinge A, ..., Stanton LW. Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis. Stem Cell Reports (2017 Apr 11)

[PubMed] [PMC free article] [DOI 10.1016/j.stemcr.2017.02.019]

85. Burbulla LF, ..., Krainc D. A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson's disease. Sci Transl Med (2019 Oct 16)

[PubMed] [PMC free article] [DOI 10.1126/scitranslmed.aau6870]

86. Cai J, ..., Iacovitti L. A stress-free strategy to correct point mutations in patient iPS cells. Stem Cell Res (2021 May)

[PubMed] [PMC free article] [DOI 10.1016/j.scr.2021.102332]

87. Candelario KM, ..., Steindler DA. Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cells. J Comp Neurol (2020 May)

[PubMed] [DOI 10.1002/cne.24819]

88. Cantley W, ..., Kaplan DL. Functional and Sustainable 3D Human Neural Network Models from Pluripotent Stem Cells. ACS Biomater Sci Eng (2018 Dec 10)

[PubMed] [PMC free article] [DOI 10.1021/acsbiomaterials.8b00622]

89. Chen MZ, ..., Hatters DM. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun (2017 Sep 7)

[PubMed] [PMC free article] [DOI 10.1038/s41467-017-00203-5]

90. Chen V, ..., Chiba-Falek O. The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations. Hum Mol Genet (2020 Nov 4)

[PubMed] [PMC free article] [DOI 10.1093/hmg/ddaa183] [Related Cell Line IDs: ND34391, ND50050, ND50085]

91. Connolly B, ..., Subramanian RR. SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency. J Nucleic Acids (2018)

[PubMed] [PMC free article] [DOI 10.1155/2018/8247935]

92. Cuddy LK, ..., Mazzulli JR. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. Neuron (2019 Dec 4)

[PubMed] [PMC free article] [DOI 10.1016/j.neuron.2019.09.001]

93. Drabik K, ..., Szczepanowska J. Effect of Chronic Stress Present in Fibroblasts Derived from Patients with a Sporadic Form of AD on Mitochondrial Function and Mitochondrial Turnover. Antioxidants (Basel) (2021 Jun 10)

[PubMed] [PMC free article] [DOI 10.3390/antiox10060938]

94. Drachev LA, ..., Skulachev VP. Reconstitution of biological molecular generators of electric current. H+-ATPase. J Biol Chem (1976 Nov 25)


95. Dzamko N, ..., Halliday GM. Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology. Acta Neuropathol (2017 Feb)

[PubMed] [PMC free article] [DOI 10.1007/s00401-016-1648-8]

96. Fog CK, ..., Kirkegaard T. The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase. EBioMedicine (2018 Dec)

[PubMed] [PMC free article] [DOI 10.1016/j.ebiom.2018.11.037] [Related Cell Line IDs: ND34263]

97. Fox LM, ..., Yamamoto A. Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. Neuron (2020 Mar 4)

[PubMed] [PMC free article] [DOI 10.1016/j.neuron.2019.12.003] [Related Cell Line IDs: ND33947]

98. García-León JA, ..., Verfaillie CM. Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells. Nat Protoc (2020 Nov)

[PubMed] [DOI 10.1038/s41596-020-0395-4]

99. Gaweda-Walerych K, ..., Zekanowski C. Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency. Front Mol Neurosci (2021)

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